Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037671 | 0.96 | RARB (0.49) | RARBRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL785042 | 0.95 | RAB9A (0.51) | RARBRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL10500743 | 0.90 | RARB (0.55) | RARBRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL10501926 | 0.89 | RARB (0.61) | RARBRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL10501532 | 0.87 | RAB9A (0.54) | RARBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL10501354 | 0.87 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL10501562 | 0.87 | RARB (0.63) | RARBRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL10559916 | 0.86 | RARB (0.57) | RARBRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL8454712 | 0.85 | RARB (0.56) | RARBRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL5354918 | 0.85 | RARB (0.64) | RARBRAB9ANPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160790-B1 | BIPYRIMIDINYL DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1989-08-16 | — | — | EP | disclosed |
| US-4609485-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1986-09-02 | — | — | US | disclosed |
| EP-0160790-A2 | Bipyrimidinyl derivatives and liquid crystal compositions containing them | Chisso Corporation (JP) | 1985-11-13 | — | — | EP | disclosed |