Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 3/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502825 | 0.87 | TOP2A (0.46) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10502264 | 0.83 | POLB (0.46) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10502880 | 0.77 | POLB (0.53) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10501647 | 0.77 | POLB (0.44) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10503399 | 0.73 | TOP2A (0.44) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL11750169 | 0.71 | TOP2A (0.38) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10912009 | 0.71 | TOP2A (0.38) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10502223 | 0.70 | TOP2A (0.46) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10477225 | 0.70 | TOP2A (0.48) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10501584 | 0.70 | TOP2A (0.35) | POLBNPC1MITFDNMT1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172632-B1 | Benzopyrano[4,3,2-cd]indazole compounds, processes for their production and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1989-08-30 | — | — | EP | claimed |
| US-4604390-A | FUNGICIDES, ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | claimed |
| EP-0172632-B1 | Benzopyrano[4,3,2-cd]indazole compounds, processes for their production and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4604390-A | FUNGICIDES, ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0172632-A1 | Benzopyrano[4,3,2-cd]indazole compounds, processes for their production and pharmaceutical compositions comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |