Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 5/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621981 | 0.76 | CRHBP (0.59) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL9621983 | 0.76 | CRHBP (0.59) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL22833791 | 0.74 | MEN1 (0.55) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL10637670 | 0.72 | MAPK1 (0.55) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL10925579 | 0.72 | SMN1; SMN2 (0.60) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL10500943 | 0.72 | CRHBP (0.36) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL9739709 | 0.72 | CRHBP (0.54) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL10926838 | 0.71 | CRHBP (0.47) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL10498926 | 0.71 | CRHBP (0.83) | LMNAALDH1A1CRHBPCRHR2KMT2A | |
| SCHEMBL10501638 | 0.70 | MAPK1 (0.58) | LMNAALDH1A1CRHBPCRHR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797484-A | REACTING GUANIDINE DERIVATIVE WITH SULPHONYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |