Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 5/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621981 | 1.00 | CRHBP (0.59) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL9621876 | 0.89 | CRHBP (0.52) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL9621874 | 0.89 | CRHBP (0.52) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL10926838 | 0.86 | CRHBP (0.47) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL9739709 | 0.81 | CRHBP (0.54) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL10637670 | 0.81 | MAPK1 (0.55) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL10925579 | 0.81 | SMN1; SMN2 (0.60) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL9621901 | 0.80 | CRHBP (0.43) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL9621906 | 0.80 | CRHBP (0.43) | CRHBPCRHR2LMNAALDH1A1KMT2A | |
| SCHEMBL10504756 | 0.77 | LMNA (0.50) | CRHBPCRHR2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470430-A1 | Process for the preparation of oxyguanidins | BAYER AG (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-4988379-A | Pre- and postemergent | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4880932-A | PLANT GROWTH REGULATORS, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-11-14 | — | — | US | disclosed |
| EP-0121082-B1 | GUANIDIN DERIVATIVES | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| US-4844730-A | PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| US-4840661-A | Sulphonyliso(thio)urea derivatives and herbicidal use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0173314-B1 | BENZODISULTAME | BAYER AG (DE) | 1989-04-12 | — | — | EP | disclosed |
| US-4802910-A | Herbicidal acylated sulphonylguanidines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-07 | — | — | US | disclosed |
| EP-0173957-B1 | SULFONYLISO(THIO) UREA DERIVATIVES | BAYER AG (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4797484-A | REACTING GUANIDINE DERIVATIVE WITH SULPHONYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0173958-A2 | 1-(2-Oxyaminocarbonylphenylsulfonyl)-3-heteroaryl ureas | BAYER AG (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0173314-A2 | Benzodisultame | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173318-A1 | Fluoralkoxyphenylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173311-A1 | Method for the preparation of sulfonyl iso(thio) ureas | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173316-A2 | 1-(2-Oxyaminosulfonylphenylsulfonyl)-3-heteroaryl-iso-(thio)-ureas | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173317-A1 | Unsymmetrical sulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173323-A1 | Amidinoazoles | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173319-A1 | Substituted arylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173320-A1 | Substituted carbonylphenylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0121082-A1 | Guanidin derivatives | BAYER AG (DE) | 1984-10-10 | — | — | EP | disclosed |