Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568773 | 0.93 | LDHA (0.54) | LTA4HEPHX2LDHASIGMAR1 | |
| SCHEMBL29549524 | 0.93 | LDHA (0.54) | LTA4HEPHX2LDHASIGMAR1 | |
| SCHEMBL29549313 | 0.92 | LDHA (0.55) | LTA4HEPHX2LDHAALOX15SIGMAR1 | |
| SCHEMBL29370506 | 0.85 | HTR1A (0.59) | LTA4HTRPV1ALOX15 | |
| SCHEMBL299310 | 0.85 | HTR1A (0.59) | LTA4HTRPV1ALOX15 | |
| SCHEMBL1286871 | 0.85 | HTR1A (0.59) | LTA4HTRPV1ALOX15 | |
| SCHEMBL28162513 | 0.85 | HTR1A (0.59) | LTA4HTRPV1ALOX15 | |
| SCHEMBL29549298 | 0.85 | HTR1A (0.59) | LTA4HTRPV1ALOX15 | |
| SCHEMBL3393167 | 0.85 | HTR1A (0.59) | LTA4HTRPV1ALOX15 | |
| SCHEMBL28516417 | 0.84 | HTR1A (0.58) | LTA4HTRPV1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149544-B1 | PHARMACEUTICAL PRODUCTS PROVIDING ENHANCED ANALGESIA | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-13 | — | — | EP | disclosed |
| EP-0149544-A2 | Pharmaceutical products providing enhanced analgesia | THE PROCTER & GAMBLE COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |