Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505053 | 0.89 | LMNA (0.49) | TP53KMT2ALMNATDP1PTGS2 | |
| SCHEMBL10504416 | 0.87 | LMNA (0.54) | TP53KMT2ALMNATDP1PTGS2 | |
| Hydrochloric Acid SCHEMBL11490589 | 0.82 | KMT2A (0.56) | TP53KMT2ALMNATDP1CYP3A4 | |
| SCHEMBL10504187 | 0.81 | LMNA (0.47) | TP53KMT2ALMNATDP1PTGS2 | |
| SCHEMBL10503599 | 0.80 | LMNA (0.53) | KMT2ALMNATDP1PTGS2MEN1 | |
| SCHEMBL10503724 | 0.79 | PTGS2 (0.52) | TP53KMT2ALMNATDP1PTGS2 | |
| SCHEMBL11344390 | 0.75 | PTGS2 (0.71) | TP53KMT2ALMNATDP1PTGS2 | |
| SCHEMBL30593451 | 0.75 | PTGS2 (0.71) | TP53KMT2ALMNATDP1PTGS2 | |
| SCHEMBL10503671 | 0.75 | KMT2A (0.50) | TP53KMT2ALMNATDP1PTGS2 | |
| SCHEMBL11520899 | 0.74 | LMNA (0.58) | TP53KMT2ALMNATDP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200615-B1 | ANTHRANILIC ACID ESTER DERIVATIVES AND ANTI-INFLAMMATORY AND ANALGESIC EXTERNAL PREPARATIONS CONTAINING THE SAME | SHISEIDO COMPANY LIMITED (JP) | 1989-08-16 | — | — | EP | disclosed |
| EP-0200615-A1 | Anthranilic acid ester derivatives and anti-inflammatory and analgesic external preparations containing the same | SHISEIDO COMPANY LIMITED (JP) | 1986-11-05 | — | — | EP | disclosed |