SCHEMBL1050408

SCHEMBL1050408

CCCCCCCOP(=S)(OCCCCCCC)SCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 13/20 0.53
LPAR2 Q9HBW0 11/20 0.53
LPAR1 Q92633 8/20 0.44
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LPAR6 P43657 3/20 0.38
LPAR4 Q99677 3/20 0.38
LPAR5 Q9H1C0 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1050405 1.00 LPAR3 (0.53) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL6691428 1.00 LPAR3 (0.53) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL28355615 1.00 LPAR3 (0.53) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL28359116 1.00 LPAR3 (0.53) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL28359216 1.00 LPAR3 (0.53) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL1044782 1.00 LPAR3 (0.53) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL252445 0.98 LPAR3 (0.50) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL28844504 0.94 LPAR3 (0.52) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL5015029 0.92 LPAR3 (0.44) LPAR3LPAR2LPAR1ALDH1A1CYP3A4
SCHEMBL1971492 0.90 CYP3A4 (0.45) LPAR3LPAR2LPAR1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110643415-B Open gear oil composition using regenerated base oil and preparation method thereof 新疆福克油品股份有限公司 2022-07-29 CN disclosed
CN-110643415-A Open gear oil composition using regenerated base oil and preparation method thereof 新疆福克油品股份有限公司 2020-01-03 CN disclosed
US-9222053-B2 Lubricating composition SHELL OIL COMPANY (US) 2015-12-29 US disclosed
US-20130017982-A1 LUBRICATING OIL COMPOSITION SHELL OIL COMPANY (US) 2013-01-17 US disclosed
US-8293692-B2 Lubricating oil composition SHELL OIL COMPANY (US) 2012-10-23 US disclosed
US-20120142568-A1 LUBRICATING COMPOSITION SHELL OIL COMPANY 2012-06-07 US disclosed
EP-2454351-A1 LUBRICATING COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2012-05-23 EP disclosed
WO-2011006755-A1 LUBRICATING COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2011-01-20 WO disclosed
WO-2010069986-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-24 WO disclosed
US-20090312209-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) 2009-12-17 US disclosed
EP-2041250-A1 LUBRICATING OIL COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2009-04-01 EP disclosed
WO-2008009704-A1 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2008-01-24 WO disclosed
US-20040204325-A1 Transmission fluid compositions for automobiles NIPPON OIL CORPORATION 2004-10-14 US disclosed
US-20040192562-A1 Lubricating oil composition NIPPON OIL CORPORATION 2004-09-30 US disclosed