Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359116 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1050408 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1044782 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28355615 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28359216 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL6691428 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1050405 | 0.92 | LPAR3 (0.53) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL252445 | 0.90 | LPAR3 (0.50) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28844504 | 0.86 | LPAR3 (0.52) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8997333 | 0.86 | ALDH1A1 (0.57) | LPAR3LPAR2ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116874-A | AROMATIC AMINE, ALKYLPHENOL, TRIESTER OF DITHIOPHOSPHORIC ACID | NIPPON OIL CO., LTD. (JP) | 1978-09-26 | — | — | US | claimed |
| US-20080312112-A1 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction | LYON DEVELOPMENT CORPORATION | 2008-12-18 | — | — | US | disclosed |
| US-4116874-A | AROMATIC AMINE, ALKYLPHENOL, TRIESTER OF DITHIOPHOSPHORIC ACID | NIPPON OIL CO., LTD. (JP) | 1978-09-26 | — | — | US | disclosed |