SCHEMBL252445

SCHEMBL252445

CCCCCOP(=S)(OCCCCC)SCCCCC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 11/20 0.50
LPAR2 Q9HBW0 10/20 0.50
CYP3A4 P08684 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LPAR1 Q92633 6/20 0.42
LPAR6 P43657 3/20 0.35
LPAR4 Q99677 3/20 0.35
LPAR5 Q9H1C0 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28359216 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL6691428 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL1050408 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL28359116 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL28355615 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL1050405 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL1044782 0.98 LPAR3 (0.53) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL28844504 0.92 LPAR3 (0.52) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL1971492 0.91 CYP3A4 (0.45) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10
SCHEMBL5015029 0.90 LPAR3 (0.44) LPAR3LPAR2CYP3A4ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109911-A1 FRICTION MODIFIER FOR WET CLUTCH CHEVRON ORONITE CO (US) 2026-04-23 US disclosed
WO-2024220394-A1 FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUID CHEVRON ORONITE COMPANY LLC (US) 2024-10-24 WO disclosed
WO-2024220396-A1 FRICTION MODIFIER FOR WET CLUTCH CHEVRON ORONITE COMPANY LLC (US) 2024-10-24 WO disclosed
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2023-05-25 US disclosed
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2023-02-14 US disclosed
EP-3071544-B1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2022-07-06 EP disclosed
US-11060027-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2021-07-13 US disclosed
US-20210130722-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2021-05-06 US disclosed
US-20200392406-A1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2020-12-17 US disclosed
US-10683455-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2020-06-16 US disclosed
US-6022929-A FUNCTIONALIZATION EXXON CHEMICAL PATENTS INC. (US) 2000-02-08 US disclosed
US-5814715-A LUBRICATING OIL CONCENTRATES; OIL ADDITIVES; DISPERSANTS; POLYMERIZED RAFFINATE II STREAMS USING A LEWIS ACID CATALYST AND BROMINE-CONTAINING PROMOTER EXXON CHEMICAL PATENTS INC (US) 1998-09-29 US disclosed
US-5717039-A CATALYZED REACTION OF ALPHA-OLEFIN ADDITION POLYMER WITH CARBON MONOXIDE AND WATER, ALCOHOL, OR THIOL USING TRANSITION METAL-FREE ACID CATALYST EXXON CHEMICAL PATENTS INC. (US) 1998-02-10 US disclosed
US-5703256-A Functionalization of polymers based on Koch chemistry and derivatives thereof EXXON CHEMICAL PATENTS INC. (US) 1997-12-30 US disclosed
US-5698722-A BLEND OF ADDITION POLYMER, CARBON MONOXIDE AND NUCLEOPHILIC TRAPPING AGENT EXXON CHEMICAL PATENTS INC. (US) 1997-12-16 US disclosed
US-5696064-A FROM CARBON MONOXIDE AND A NUCLEOPHILIC TRAPPING AGENT EXXON CHEMICAL PATENTS INC. (US) 1997-12-09 US disclosed
US-5663130-A Polymers derived from ethylene and 1-butene for use in the preparation of lubricant dispersant additives EXXON CHEMICAL PATENTS INC (US) 1997-09-02 US disclosed
US-5629434-A REACTION PRODUCT OF POLYMER WITH AT LEAST ONE ETHYLENIC DOUBLE BOND WITH CARBON MONOXIDE AND NUCLEOPHILIC TRAPPING AGENT; DISPERSANTS, VISCOSITY MODIFIERS EXXON CHEMICAL PATENTS INC (US) 1997-05-13 US disclosed
US-5498809-A TERMINAL ETHYLVINYLIDENE GROUPS WHICH CAN BE FUNCTIONALIZED, DISPERSANTS EXXON CHEMICAL PATENTS INC. (US) 1996-03-12 US disclosed
US-5444135-A Polymerization and functionalization with nitrogen-containing functional groups occur simultaneously EXXON CHEMICAL PATENTS INC. (US) 1995-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11060027-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 LPAR3 4767/4885LPAR2 4138/4885CYP3A4 1297/4885
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 LPAR3 4878/4885LPAR2 4787/4885CYP3A4 3582/4885
US-10683455-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 LPAR3 4767/4885LPAR2 4138/4885CYP3A4 1297/4885
US-20260109911-A1 FRICTION MODIFIER FOR WET CLUTCH SMCHD1, CLTC, CLTA LPAR3 2708/4885LPAR2 2175/4885CYP3A4 2776/4885
US-20210130722-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 LPAR3 4878/4885LPAR2 4787/4885CYP3A4 3582/4885
US-20200392406-A1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME LPO, GPX4, DUOX2 LPAR3 4767/4885LPAR2 4138/4885CYP3A4 1297/4885
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 LPAR3 4878/4885LPAR2 4787/4885CYP3A4 3582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.