Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937448 | 0.85 | AR (0.40) | ARALDH1A1HPGD | |
| SCHEMBL10505510 | 0.83 | AR (0.47) | ARGAAALDH1A1 | |
| SCHEMBL30343622 | 0.83 | AR (0.47) | ARGAAALDH1A1 | |
| SCHEMBL3079041 | 0.82 | MAOB (0.46) | — | |
| SCHEMBL1132618 | 0.82 | PIP4K2A (0.48) | PIP4K2APDE3AARPDE5AGRIN1 | |
| SCHEMBL198911 | 0.76 | ALDH1A1 (0.60) | PDE5AL3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL10518879 | 0.76 | KCNN4 (0.48) | ARGAAALDH1A1HPGDKDM4E | |
| SCHEMBL30283197 | 0.75 | SMN1; SMN2 (0.51) | ARGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5451 | 0.75 | SMN1; SMN2 (0.51) | ARGAAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL12670736 | 0.74 | TSHR (0.50) | ARGAAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096142-B1 | MICROBICIDAL SULFONYL PYRROLE | CIBA-GEIGY AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| EP-0096142-A2 | Microbicidal sulfonyl pyrrole | CIBA-GEIGY AG (CH) | 1983-12-21 | — | — | EP | disclosed |