Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510242 | 0.85 | GAA (0.42) | GAAGLAPOLBTSHRTP53 | |
| SCHEMBL10509954 | 0.85 | GLA (0.42) | GAAGLAPOLBTSHRRXRA | |
| SCHEMBL29404322 | 0.79 | GAA (0.59) | GAAGLAPOLBTSHRMAOA | |
| SCHEMBL436804 | 0.79 | GAA (0.59) | GAAGLAPOLBTSHRMAOA | |
| SCHEMBL10506895 | 0.78 | MRGPRX1 (0.41) | GAAPOLBMAOARXRAGRIN1 | |
| Hydrochloric Acid SCHEMBL8863493 | 0.77 | GAA (0.57) | GAAGLAPOLBTSHRMAOA | |
| SCHEMBL9770766 | 0.77 | CYP1A2 (0.47) | GAAPOLBTP53MAPTSMN1; SMN2 | |
| SCHEMBL9635890 | 0.77 | CYP3A4 (0.38) | GAAPOLBTSHRMAPTL3MBTL1 | |
| SCHEMBL10509673 | 0.77 | CYP1A2 (0.48) | POLBMAPTS1PR4ARKMT2A | |
| SCHEMBL12595074 | 0.76 | KMT2A (0.53) | GAAGLAPOLBTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164694-B1 | N-BENZOYL-N'-PYRIMIDINYLOXYPHENYL UREA COMPOUNDS, AND ANTITUMOROUS COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |
| US-4677110-A | N-benzoyl-N'-pyrimidinyloxyphenyl urea compounds, and antitumorous compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0164694-A2 | N-Benzoyl-N'-pyrimidinyloxyphenyl urea compounds, and antitumorous compositions containing them, and process for their preparation | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1985-12-18 | — | — | EP | disclosed |