Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599828 | 0.84 | HSD17B10 (0.58) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL16376473 | 0.84 | HSD17B10 (0.58) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL14493098 | 0.80 | ALDH1A1 (0.58) | HSD17B10ALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL23842797 | 0.80 | ALDH1A1 (0.55) | HSD17B10KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL24829947 | 0.80 | HSD17B10 (0.44) | HSD17B10VCAM1ALDH1A1TDP1LMNA | |
| SCHEMBL9808985 | 0.78 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL9808930 | 0.78 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL11381869 | 0.78 | TDP1 (0.53) | HSD17B10KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL85918 | 0.76 | HSD17B10 (1.00) | HSD17B10VCAM1KMT2AALDH1A1TDP1 | |
| SCHEMBL29360183 | 0.76 | HSD17B10 (1.00) | HSD17B10VCAM1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110396116-B | [ N, O ] bidentate nickel and palladium complex of ketone-imidazoline-2-imine ligand, and preparation method and application thereof | 东华大学 | 2020-07-28 | — | — | CN | claimed |
| CN-110396116-B | [ N, O ] bidentate nickel and palladium complex of ketone-imidazoline-2-imine ligand, and preparation method and application thereof | 东华大学 | 2020-07-28 | — | — | CN | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |