Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808985 | 0.88 | HSD17B10 (0.51) | HSD17B10VCAM1ALDH1A1TDP1CYP1A2 | |
| SCHEMBL10507366 | 0.78 | HSD17B10 (0.60) | HSD17B10VCAM1ALDH1A1TDP1CYP1A2 | |
| SCHEMBL27599828 | 0.77 | HSD17B10 (0.58) | HSD17B10VCAM1ALDH1A1TDP1CYP1A2 | |
| SCHEMBL16376473 | 0.77 | HSD17B10 (0.58) | HSD17B10VCAM1ALDH1A1TDP1KMT2A | |
| SCHEMBL9808973 | 0.75 | HSD17B10 (0.51) | HSD17B10VCAM1ALDH1A1TDP1KMT2A | |
| SCHEMBL23507272 | 0.74 | TSHR (0.49) | VCAM1ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL28257873 | 0.73 | CYP1A2 (0.64) | HSD17B10ALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL10452388 | 0.73 | HSD17B10 (0.49) | HSD17B10VCAM1ALDH1A1TDP1CYP1A2 | |
| SCHEMBL29359062 | 0.72 | TP53 (0.36) | KMT2AMEN1LMNA | |
| SCHEMBL10507359 | 0.72 | CYP1A2 (0.58) | HSD17B10ALDH1A1TDP1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |