Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508176 | 0.87 | ALPL (0.38) | TSHRPOLBRAB9AGAAALDH1A1 | |
| SCHEMBL11144994 | 0.74 | MAP2K4 (0.52) | POLBRAB9AALDH1A1MAP2K4MAPT | |
| SCHEMBL5787779 | 0.73 | NOTUM (0.43) | TSHRPOLBGAAALDH1A1LMNA | |
| SCHEMBL31057270 | 0.72 | GAA (0.45) | TSHRRAB9AGAAALDH1A1MAPT | |
| SCHEMBL10923051 | 0.71 | HSP90AA1 (0.41) | TSHRPOLBGAAALDH1A1HSP90AA1 | |
| SCHEMBL10921229 | 0.70 | HSP90AA1 (0.41) | TSHRPOLBGAAALDH1A1MAP2K4 | |
| SCHEMBL11154393 | 0.69 | ALPL (0.35) | TSHRGAAALDH1A1MAP2K4ALPL | |
| SCHEMBL3699537 | 0.68 | TSHR (0.46) | TSHRGAAALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL612875 | 0.67 | CYP3A4 (0.47) | TSHRPOLBGAAALDH1A1MAPT | |
| SCHEMBL29070096 | 0.66 | NOTUM (0.41) | TSHRPOLBGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121129-B1 | 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1989-02-01 | — | — | EP | disclosed |
| US-4726837-A | Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1988-02-23 | — | — | US | disclosed |
| US-4715889-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | disclosed |
| US-4692187-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0115808-B1 | CYCLOHEXAN-1,3-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1986-08-20 | — | — | EP | disclosed |
| EP-0104389-B1 | QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CONTROL OF UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1986-07-16 | — | — | EP | disclosed |
| US-4585881-A | 2,5-dihydro-5-aryliminopyrrole derivatives and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0121129-A1 | 2,5-Dihydro-5-arylimino-pyrroles, process for their production and their uses as herbicides | BASF Aktiengesellschaft (DE) | 1984-10-10 | — | — | EP | disclosed |
| EP-0115808-A1 | Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1984-08-15 | — | — | EP | disclosed |