Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472383 | 0.82 | GAA (0.49) | TSHRGAAALDH1A1GFERMAPT | |
| SCHEMBL942577 | 0.79 | PDE4D (0.56) | GAAALDH1A1MAPTMAPK10SMN1; SMN2 | |
| SCHEMBL20694706 | 0.79 | GRM6 (0.36) | TSHRGAAALDH1A1GFERMAPT | |
| SCHEMBL17730892 | 0.78 | TSHR (0.41) | TSHRGAAALDH1A1GFERMAPT | |
| SCHEMBL15306998 | 0.77 | GAA (0.34) | GAAALDH1A1GFERMAPTMAPK10 | |
| SCHEMBL17730533 | 0.77 | TSHR (0.40) | TSHRGAAALDH1A1GFERMAPT | |
| SCHEMBL2085520 | 0.77 | L3MBTL1 (0.38) | TSHRGAAALDH1A1GFERMAPT | |
| SCHEMBL18895830 | 0.76 | YTHDC1 (0.35) | TSHRGAAALDH1A1GFERMAPT | |
| SCHEMBL21585179 | 0.76 | SMN1; SMN2 (0.43) | GAAALDH1A1GFERMAPTMAPK10 | |
| SCHEMBL9921657 | 0.75 | HTT (0.43) | TSHRGAAALDH1A1GFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663519-B2 | Compounds useful as inhibitors of ATR kinase | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-05-30 | — | — | US | disclosed |
| US-8609669-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2013-12-17 | — | — | US | disclosed |
| WO-2012067822-A1 | PYRAZOLO [1, 5 -A] PYRIMIDIN POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | WO | disclosed |
| US-20120122888-A1 | Potassium Channel Modulators | ABBOTT LABORATORIES (US) | 2012-05-17 | — | — | US | disclosed |
| US-4950585-A | CYAN COUPLERS COMPRISING IMIDAZO(1,5-A)PYRIMIDINE COMPOUNDS; COLORFASTNESS; HEAT AND HUMIDITY RESISTANCE; COLOR PHOTOGRAPHY | KONICA CORPORATION (JP) | 1990-08-21 | — | — | US | disclosed |
| EP-0304001-A2 | Coupler for photographic use | KONICA CORPORATION (JP) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122888-A1 | Potassium Channel Modulators | KCNQ1, KCNQ2, KCNJ2 | TSHR 1117/4885GAA 3330/4885ALDH1A1 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.