⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508164 | 1.00 | — | — | |
| SCHEMBL5487108 | 0.77 | MAPT (0.47) | — | |
| SCHEMBL6745671 | 0.72 | — | — | |
| SCHEMBL23133030 | 0.72 | — | — | |
| SCHEMBL25407367 | 0.72 | — | — | |
| SCHEMBL25406639 | 0.72 | — | — | |
| SCHEMBL6591442 | 0.69 | GSK3B (0.41) | — | |
| SCHEMBL4565024 | 0.69 | GSK3B (0.39) | — | |
| SCHEMBL6591437 | 0.69 | GSK3B (0.41) | — | |
| SCHEMBL3254361 | 0.67 | GSK3B (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859228-A | Novel 5-aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones | ICI AMERICAS INC (US) | 1989-08-22 | — | — | US | disclosed |
| US-4859228-A | Novel 5-aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones | ICI AMERICAS INC (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0300882-A3 | NOVEL 5-AMINOMETHYLENE-2,4-IMIDAZOLIDINEDIONES AND 5-AMINOMETHYLENE-2-THIONOIMIDAZOLIDINE-4-ONES | ICI AMERICAS INC. (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0300882-A2 | Novel 5-Aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones | ICI AMERICAS INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0300882-A2 | Novel 5-Aminomethylene-2,4-imidazolidinediones and 5-aminomethylene-2-thionoimidazolidine-4-ones | ICI AMERICAS INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4345936-A | Imidazoles, compositions and herbicidal method | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |