Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | OGT | O15294 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508164 | 0.69 | — | — | |
| SCHEMBL6745671 | 0.69 | — | — | |
| SCHEMBL25406639 | 0.69 | — | — | |
| SCHEMBL23133030 | 0.69 | — | — | |
| SCHEMBL10508166 | 0.69 | — | — | |
| SCHEMBL25407367 | 0.69 | — | — | |
| SCHEMBL11598662 | 0.69 | GSK3B (0.36) | GSK3BCGASMAPTKDM4EBLM | |
| SCHEMBL20927303 | 0.67 | — | — | |
| SCHEMBL18606842 | 0.67 | KDM4E (0.31) | MAPTKDM4EBLMOGTUSP2 | |
| SCHEMBL11303443 | 0.66 | POLB (0.36) | GSK3BCGASMAPTKDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61027971-A | — | — | None | — | — | JP | disclosed |
| JP-8277252-A | — | — | None | — | — | JP | disclosed |
| JP-5255273-A | — | — | None | — | — | JP | disclosed |
| JP-1158090-A | — | — | None | — | — | JP | disclosed |
| US-8299293-B2 | Process for preparing α-keto acids and derivatives thereof | EVONIK DEGUSSA GMBH (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20090076302-A1 | PROCESS FOR PREPARING a-KETO ACIDS AND DERIVATIVES THEREOF | EVONIK DEGUSSA GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| JP-H08277252-A | PRODUCTION OF ACETYLATED AMINO ACID DERIVATIVE | KAWAKEN FINE CHEM CO LTD | 1996-10-22 | — | — | JP | disclosed |
| JP-H05255273-A | PRODUCTION OF 5-ALKYLHYDANTOIN DERIVATIVE | AJINOMOTO CO INC | 1993-10-05 | — | — | JP | disclosed |
| US-4871552-A | 5-ALKYLIDENE OR 5-HYDROXY-5-ALKYL DERIVATIVES | W. R. GRACE & CO.-CONN. (US) | 1989-10-03 | — | — | US | disclosed |
| JP-H01158090-A | METHOD FOR STABILIZING ULTRAVIOLET RAY ABSORBER | AJINOMOTO CO INC | 1989-06-21 | — | — | JP | disclosed |
| US-4744990-A | NUTRIENTS FOR ANIMALS | W. R. GRACE & CO. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0261982-A1 | Animal food supplements | W.R. GRACE & CO. (US) | 1988-03-30 | — | — | EP | disclosed |
| JP-S6127971-A | PREPARATION OF 5-ALKYLIDENEHYDANTOIN | SHOWA DENKO KK | 1986-02-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076302-A1 | PROCESS FOR PREPARING a-KETO ACIDS AND DERIVATIVES THEREOF | BCKDK, KHK, ADSL | GSK3B 2653/4885CGAS 3094/4885MAPT 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.