Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047141 | 0.87 | RAB9A (0.53) | SRD5A2SRD5A1ALDH1A1MRGPRX4MEN1 | |
| SCHEMBL31501880 | 0.87 | RAB9A (0.53) | SRD5A2SRD5A1ALDH1A1MRGPRX4MEN1 | |
| SCHEMBL7879867 | 0.85 | SRD5A2 (0.51) | SRD5A2SRD5A1ALDH1A1IDO1MMP2 | |
| SCHEMBL10509285 | 0.83 | ALDH1A1 (0.50) | SRD5A2SRD5A1ALDH1A1IDO1MMP2 | |
| SCHEMBL10506123 | 0.83 | SRD5A2 (0.43) | SRD5A2SRD5A1ALDH1A1IDO1MMP2 | |
| SCHEMBL1653144 | 0.82 | SRD5A2 (0.64) | SRD5A2SRD5A1ALDH1A1IDO1MRGPRX4 | |
| SCHEMBL10508127 | 0.81 | SRD5A2 (0.48) | SRD5A2SRD5A1ALDH1A1IDO1MRGPRX4 | |
| SCHEMBL10507108 | 0.78 | CDK1 (0.44) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7431717 | 0.76 | MAOB (0.50) | ALDH1A1MRGPRX4MEN1KMT2AKDM4E | |
| SCHEMBL18553954 | 0.75 | ALDH1A1 (0.47) | SRD5A2SRD5A1ALDH1A1MRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835175-A | Indole derivatives pharmaceutical preparations based thereon, and β-receptor stimulation therewith | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |