Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699661 | 0.73 | ALDH1A1 (0.45) | MAPTKDM4EGAAHDAC2HDAC1 | |
| SCHEMBL11500098 | 0.73 | PTGIR (0.43) | RIPK1 | |
| SCHEMBL24755747 | 0.72 | MAPT (0.41) | MAPTKDM4EGAAHDAC2HDAC1 | |
| SCHEMBL977627 | 0.72 | PTGER4 (0.47) | MAPTKDM4EGAAHDAC2HDAC1 | |
| SCHEMBL30693377 | 0.72 | PTGER4 (0.47) | MAPTKDM4EGAAHDAC2HDAC1 | |
| SCHEMBL5487812 | 0.70 | HDAC3 (0.40) | MAPTKDM4EGAAHDAC2HDAC1 | |
| SCHEMBL29938610 | 0.69 | HPGD (0.54) | MAPTKDM4EGAAALDH1A1LMNA | |
| SCHEMBL15846026 | 0.68 | KDM4E (0.54) | KDM4EGAAALDH1A1KMT2ALMNA | |
| SCHEMBL3798519 | 0.68 | ALDH1A1 (0.53) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23493020 | 0.68 | ALDH1A1 (0.53) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1056666-A | — | — | None | — | — | JP | disclosed |
| JP-S6456666-A | CYCLOPROPYLMETHOXY-2-MERCAPTOBENZIMIDAZOLE AND PRODUCTION THEREOF | TOKYO TANABE CO | 1989-03-03 | — | — | JP | disclosed |