Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 11/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26803231 | 0.82 | MAPT (0.43) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL27841531 | 0.81 | CYP1A2 (0.43) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL6131913 | 0.78 | MAPT (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11699661 | 0.76 | ALDH1A1 (0.45) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL16742379 | 0.75 | ALDH1A1 (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL24755747 | 0.74 | MAPT (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL10697594 | 0.71 | ALDH1A1 (0.46) | MAPTGAAALDH1A1LMNACYP1A2 | |
| SCHEMBL10508182 | 0.70 | MAPT (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL7375160 | 0.69 | KDM4E (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL30128490 | 0.69 | KDM4E (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190182-C | Intermediates for use in oxidative hair coloring | P & G KLEROL INC (US) | 2005-02-23 | — | — | CN | claimed |
| CN-1404384-A | Novel primary intermediates for use in oxidative hair dyeing | P & G KLEROL INC (US) | 2003-03-19 | — | — | CN | claimed |
| US-7282067-B2 | Composition for dyeing keratin fibres, containing an alcohol oxidase, and process using this composition | L'OREAL (FR) | 2007-10-16 | — | — | US | disclosed |
| CN-1190182-C | Intermediates for use in oxidative hair coloring | P & G KLEROL INC (US) | 2005-02-23 | — | — | CN | disclosed |
| CN-1404384-A | Novel primary intermediates for use in oxidative hair dyeing | P & G KLEROL INC (US) | 2003-03-19 | — | — | CN | disclosed |