Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764907 | 1.00 | HTT (0.43) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10509267 | 0.98 | HTT (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10510658 | 0.98 | HTT (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10509273 | 0.98 | HTT (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10509270 | 0.98 | HTT (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10510655 | 0.98 | HTT (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10509705 | 0.95 | APEX1 (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10509709 | 0.95 | APEX1 (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL10509699 | 0.95 | APEX1 (0.44) | HTTAPEX1BLMTSHRTP53 | |
| SCHEMBL30876267 | 0.80 | APEX1 (0.47) | HTTAPEX1BLMTSHRFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213506-B1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1989-02-15 | — | — | EP | claimed |
| EP-0213506-A1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1987-03-11 | — | — | EP | claimed |
| US-4621097-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1986-11-04 | — | — | US | claimed |
| EP-0213506-B1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1989-02-15 | — | — | EP | disclosed |
| EP-0213506-A1 | Saturated cycloalkyl[c]pyrrole-2(1H)-acetic acid amides and derivatives thereof | WARNER-LAMBERT COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4621097-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1986-11-04 | — | — | US | disclosed |