Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 6/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509273 | 0.81 | HTT (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10509699 | 0.81 | APEX1 (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10510655 | 0.81 | HTT (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10510658 | 0.81 | HTT (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10509705 | 0.81 | APEX1 (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10509267 | 0.81 | HTT (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10509270 | 0.81 | HTT (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10509709 | 0.81 | APEX1 (0.44) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10764907 | 0.80 | HTT (0.43) | APEX1BLMTSHRRAB9APER2 | |
| SCHEMBL10508253 | 0.80 | HTT (0.43) | APEX1BLMTSHRRAB9APER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099435-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-05-16 | — | — | WO | disclosed |
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |