Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508329 | 1.00 | ACE (0.60) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10507852 | 0.96 | ACE (0.59) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10507846 | 0.96 | ACE (0.59) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9814639 | 0.95 | ACE (0.56) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10510787 | 0.95 | ACE (0.58) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10508472 | 0.93 | ACE (0.62) | ACERAB9AFKBP1AKLK5F2 | |
| SCHEMBL10508467 | 0.93 | ACE (0.62) | ACERAB9AFKBP1AKLK5F2 | |
| SCHEMBL9814597 | 0.92 | ACE (0.56) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9501238 | 0.89 | FKBP1A (0.54) | ACEMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9814479 | 0.88 | ACE (0.58) | ACERAB9AFKBP1AKLK5F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172458-B1 | NOVEL BIOLOGICALLY ACTIVE COMPOUND HAVING ANTI-PROLYL ENDOPEPTIDASE ACTIVITY | SUNTORY LIMITED (JP) | 1989-11-02 | — | — | EP | disclosed |
| US-4743616-A | ANTIAMNESIA AGENTS | SUNTORY LIMITED (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0172458-A2 | Novel biologically active compound having anti-prolyl endopeptidase activity | SUNTORY LIMITED (JP) | 1986-02-26 | — | — | EP | disclosed |