Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500400 | 0.89 | ACE (0.52) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL10508329 | 0.89 | ACE (0.60) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL10508327 | 0.89 | ACE (0.60) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL10507852 | 0.86 | ACE (0.59) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL10507846 | 0.86 | ACE (0.59) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL9501704 | 0.86 | PREP (0.53) | FFAR1 | |
| SCHEMBL9814639 | 0.85 | ACE (0.56) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL10510787 | 0.85 | ACE (0.58) | FKBP1AACEMEN1KMT2ANPC1 | |
| SCHEMBL10508467 | 0.82 | ACE (0.62) | FKBP1AACERAB9AF2KLK5 | |
| SCHEMBL10508472 | 0.82 | ACE (0.62) | FKBP1AACERAB9AF2KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232849-B1 | PYRROLIDINEAMIDE DERIVATIVE OF ACYLAMINO ACID, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5198458-A | Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| US-4826870-A | CURING AMNESIA | SUNTORY LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0232849-A2 | Pyrrolidineamide derivative of acylamino acid, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1987-08-19 | — | — | EP | disclosed |