Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125260 | 0.89 | PNMT (0.48) | PNMTADRA2AGRIN2BMEN1KMT2A | |
| SCHEMBL16650443 | 0.86 | PNMT (0.46) | PNMTADRA2AGRIN2BAKR1B1MEN1 | |
| SCHEMBL7390944 | 0.86 | GRIN2B (0.41) | PNMTADRA2AGRIN2BMEN1KMT2A | |
| SCHEMBL6493305 | 0.85 | ITGB3 (0.50) | PNMTADRA2AGRIN2BAKR1B1MAPT | |
| SCHEMBL6492849 | 0.85 | ITGB3 (0.50) | PNMTADRA2AGRIN2BAKR1B1MAPT | |
| SCHEMBL8426665 | 0.84 | PNMT (0.41) | PNMTADRA2AGRIN2BAKR1B1MEN1 | |
| SCHEMBL6490826 | 0.81 | MEN1 (0.41) | PNMTADRA2AGRIN2BMEN1KMT2A | |
| SCHEMBL8425944 | 0.81 | PNMT (0.38) | PNMTADRA2AGRIN2BMEN1KMT2A | |
| SCHEMBL8424903 | 0.81 | PNMT (0.38) | PNMTADRA2AGRIN2BMEN1KMT2A | |
| SCHEMBL8428904 | 0.81 | GRIN2B (0.38) | PNMTADRA2AGRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306706-A | Difunctional compound targeting androgen receptor protein degradation and application thereof | 上海壹迪生物技术有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2019037742-A1 | IMIDAZOLONE ANDROGEN RECEPTOR ANTAGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海时莱生物技术有限公司 | 2019-02-28 | — | — | WO | disclosed |
| EP-0145067-B1 | DERIVATIVES OF 2,2'-IMINOBISETHANOL | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-25 | — | — | EP | disclosed |
| US-4654362-A | CARDIOVASCULAR DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1987-03-31 | — | — | US | disclosed |
| EP-0145067-A2 | Derivatives of 2,2'-iminobisethanol | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-06-19 | — | — | EP | disclosed |