SCHEMBL1050859

SCHEMBL1050859

PCC([N]C(CP)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.36
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 1/20 0.33
KIF11 P52732 4/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8048324 0.72 MAPK1 (0.39) KCNN4TSHRALDH1A1TAAR1CYP2C19
SCHEMBL766983 0.70 KIF11 (0.46) KCNN4TSHRALDH1A1TAAR1CYP2C19
SCHEMBL27979164 0.69 KCNN4 (0.52) KCNN4TSHRALDH1A1TAAR1CYP2C19
SCHEMBL10995938 0.69 KIF11 (0.44) KCNN4TSHRALDH1A1TAAR1CYP2C19
Hydrochloric Acid SCHEMBL660294 0.69 KIF11 (0.44) KCNN4TSHRALDH1A1TAAR1CYP2C19
Water SCHEMBL11171777 0.69 KIF11 (0.44) KCNN4TSHRALDH1A1TAAR1CYP2C19
Bromide SCHEMBL110208 0.69 KIF11 (0.44) KCNN4TSHRALDH1A1TAAR1CYP2C19
SCHEMBL7211127 0.69 KCNN4 (0.40) KCNN4TSHRALDH1A1TAAR1CYP2C19
Iodide SCHEMBL660827 0.69 KIF11 (0.44) KCNN4TSHRALDH1A1TAAR1CYP2C19
SCHEMBL12422641 0.67 CYP2C19 (0.52) KCNN4TSHRALDH1A1TAAR1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2032115-B1 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS BV (NL) 2021-07-21 EP disclosed
EP-2454312-B1 RESINS AND COATING COMPOSITIONS DSM IP ASSETS BV (NL) 2017-03-01 EP disclosed
US-8999494-B2 Resins and coating compositions DSM IP ASSETS B.V. (NL) 2015-04-07 US disclosed
US-8394500-B2 Compositions based on hyperbranched condensation polymers and novel hyperbranched condensation polymers DSM IP ASSETS B.V. (NL) 2013-03-12 US disclosed
US-20120183749-A1 RESINS AND COATING COMPOSITIONS COVESTRO (NETHERLANDS) B.V. (NL) 2012-07-19 US disclosed
EP-2454312-A1 RESINS AND COATING COMPOSITIONS DSM IP Assets B.V. (NL) 2012-05-23 EP disclosed
WO-2011007003-A1 RESINS AND COATING COMPOSITIONS DSM IP ASSETS B.V. (NL) 2011-01-20 WO disclosed
US-20100069601-A1 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS B.V. (NL) 2010-03-18 US disclosed
EP-2032115-A2 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSMIP Assets B.V. (NL) 2009-03-11 EP disclosed
WO-2007144189-A2 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS B.V. (NL) 2007-12-21 WO disclosed