Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057047 | 0.83 | LMNA (0.45) | MAPK1KCNN4ALDH1A1KIF11TAAR1 | |
| SCHEMBL7764290 | 0.77 | KCNN4 (0.43) | MAPK1KCNN4TSHRALDH1A1KIF11 | |
| SCHEMBL7001871 | 0.75 | CYP1A2 (0.52) | MAPK1TSHRKIF11TAAR1CYP1A2 | |
| SCHEMBL3341600 | 0.73 | TDP1 (0.36) | MAPK1KCNN4TSHRALDH1A1KIF11 | |
| SCHEMBL5928060 | 0.73 | TSHR (0.39) | MAPK1KCNN4TSHRALDH1A1KIF11 | |
| SCHEMBL5614716 | 0.73 | KCNN4 (0.40) | MAPK1KCNN4TSHRALDH1A1KIF11 | |
| SCHEMBL766983 | 0.72 | KIF11 (0.46) | MAPK1KCNN4TSHRALDH1A1KIF11 | |
| SCHEMBL1050859 | 0.72 | KCNN4 (0.36) | MAPK1KCNN4TSHRALDH1A1KIF11 | |
| SCHEMBL6685383 | 0.72 | MAPK1 (0.38) | MAPK1KCNN4TSHRALDH1A1TAAR1 | |
| SCHEMBL7211127 | 0.70 | KCNN4 (0.40) | MAPK1KCNN4TSHRALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020532-A | Process for the preparation of aldehydes employing catalyst compositions based on rhodium complexes containing diphosphine ligands | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| US-5922634-A | HYDROFORMYLATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-13 | — | — | US | disclosed |