Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 3/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138943 | 0.82 | KDR (0.48) | HIF1ACREBBPPDE2APRMT5WDR77 | |
| SCHEMBL9911757 | 0.81 | PTGS2 (0.46) | HIF1APTGIRCREBBPPDE2APRMT5 | |
| SCHEMBL12175373 | 0.81 | CREBBP (0.62) | HIF1ACREBBPPTGS2NPC1RAB9A | |
| SCHEMBL23402261 | 0.79 | HIF1A (0.42) | HIF1APTGIRCREBBPPDE2APRMT5 | |
| SCHEMBL14937976 | 0.79 | HIF1A (0.42) | HIF1APTGIRCREBBPPDE2APRMT5 | |
| SCHEMBL16110414 | 0.79 | RAB9A (0.46) | HIF1APTGIRCREBBPPTGS2NPC1 | |
| SCHEMBL23400268 | 0.79 | CREBBP (0.45) | HIF1APTGIRCREBBPPTGS2NPC1 | |
| SCHEMBL13737154 | 0.79 | NPC1 (0.59) | CREBBPPTGS2NPC1RAB9AMAPT | |
| SCHEMBL3562130 | 0.79 | HTR2A (0.47) | HIF1APTGIRCREBBPPDE2APRMT5 | |
| SCHEMBL5966750 | 0.79 | CREBBP (0.45) | HIF1APTGIRCREBBPPTGS2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299407-A1 | 1H-pyrazole-1-alkanamides and preparation useful as antiarrhythmic agents | STERLING DRUG INC. (US) | 1989-01-18 | — | — | EP | disclosed |