SCHEMBL10508671

SCHEMBL10508671

CCO[Si](C)(N(CC)C(C)=O)N(CC)C(C)=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11130254 0.78
SCHEMBL15259510 0.76 ALDH1A1 (0.33) ALDH1A1LMNAHSD17B10
SCHEMBL203529 0.74 CHRM1 (0.33) ALDH1A1
SCHEMBL11678374 0.74 CHRM1 (0.38) ALDH1A1
SCHEMBL9422287 0.74 CHRM1 (0.33) ALDH1A1
SCHEMBL22769511 0.71 CHRM2 (0.33)
SCHEMBL9578283 0.68 SOAT1 (0.33) ALDH1A1
SCHEMBL28790102 0.67 CHRM1 (0.32) ALDH1A1
SCHEMBL9850901 0.67 CHRM1 (0.32) ALDH1A1
SCHEMBL27981313 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0193739-B1 PROCESS FOR THE PREPARATION OF AMINOSILANES BAYER AG (DE) 1989-02-15 EP disclosed
US-4739088-A REACTING AMIDES WITH ALCOHOLIC METAL SALTS; REMOVING ALCOHOL; REACTING WITH ORGANOSILANES BAYER AKTIENGESELLSCHAFT (DE) 1988-04-19 US disclosed
EP-0193739-A1 Process for the preparation of aminosilanes BAYER AG (DE) 1986-09-10 EP disclosed