Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506240 | 0.88 | TSHR (0.62) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL183822 | 0.86 | TSHR (0.51) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL28313658 | 0.84 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL28312829 | 0.84 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL183721 | 0.81 | TSHR (0.49) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL10506587 | 0.81 | TSHR (0.56) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL10506509 | 0.80 | TSHR (0.60) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL10508554 | 0.79 | TSHR (0.58) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL10972557 | 0.79 | TSHR (0.58) | TSHRALDH1A1TDP1SMN1; SMN2TP53 | |
| SCHEMBL10509287 | 0.78 | TSHR (0.53) | TSHRALDH1A1TDP1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155810-B1 | N-(OMEGA-GLYCIDOXYALKYL)-SUBSTITUTED AMIDE COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0155810-A2 | N-(omega-glycidoxyalkyl)-substituted amide compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-25 | — | — | EP | disclosed |