Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384876 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MEN1KMT2APDE10A | |
| SCHEMBL10102664 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1MEN1KMT2APTGDR2 | |
| SCHEMBL20081370 | 0.81 | PDE10A (0.61) | KDM4EALDH1A1MEN1KMT2APDE10A | |
| SCHEMBL1882100 | 0.81 | PDE10A (0.56) | KDM4EALDH1A1MEN1KMT2APDE10A | |
| SCHEMBL3625129 | 0.80 | KMT2A (0.69) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL24597657 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2APDE10A | |
| SCHEMBL4583699 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL30301321 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4915121 | 0.79 | PDE10A (0.53) | KDM4EALDH1A1MEN1KMT2APDE10A | |
| Acridine SCHEMBL28058942 | 0.78 | ALDH1A1 (0.57) | KDM4EALDH1A1MEN1KMT2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210084-B1 | AMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-02-08 | — | — | EP | disclosed |