Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301321 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28992953 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL26969215 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL3625129 | 0.81 | KMT2A (0.69) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28992969 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL24597657 | 0.80 | KDM4E (0.67) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL10473740 | 0.80 | ALDH1A1 (0.66) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL10509302 | 0.79 | KDM4E (0.65) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27524110 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28231528 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1952797-A1 | Use of a cosmetic composition comprising NMDA receptor agonists for cosmetic skin treatment | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2008-08-06 | — | — | EP | claimed |
| EP-1800672-A1 | Pharmaceutical composition and the use therof for the treatment of dermatoses | Dr. August Wolff GmbH & Co. (DE) | 2007-06-27 | — | — | EP | claimed |
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-7858560-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
| EP-1952797-A1 | Use of a cosmetic composition comprising NMDA receptor agonists for cosmetic skin treatment | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1800672-A1 | Pharmaceutical composition and the use therof for the treatment of dermatoses | Dr. August Wolff GmbH & Co. (DE) | 2007-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | ALDH1A1 4360/4885KDM4E 1669/4885KMT2A 2736/4885 |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CHLSN, PTMS, SRMS | ALDH1A1 4064/4885KDM4E 3796/4885KMT2A 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.