Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | RARB | P10826 | 6/20 | 0.55 |
| ▸ | RARA | P10276 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513846 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10512156 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10511667 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9819140 | 0.98 | ALDH1A1 (0.67) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL27594237 | 0.98 | ALDH1A1 (0.66) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL7029715 | 0.93 | RAB9A (0.58) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9850160 | 0.86 | MAPT (0.79) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10346280 | 0.86 | MAPT (0.79) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9840084 | 0.86 | MAPT (0.79) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9850283 | 0.86 | MAPT (0.79) | ALDH1A1MAPTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1214014-C | HIV inhibiting pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2005-08-10 | — | — | CN | disclosed |
| CN-1295564-A | HIV inhibiting pyrimidine derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2001-05-16 | — | — | CN | disclosed |
| EP-0313284-A2 | 2,5-Diphenyl pyrimidine compounds and liquid crystal compositions containing them | Chisso Corporation (JP) | 1989-04-26 | — | — | EP | disclosed |