Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631435 | 1.00 | RXFP1 (0.49) | RXFP1SLC6A2PDE4DKCNH2HTR2A | |
| Florifenine SCHEMBL29400044 | 0.99 | SLC6A2 (0.49) | RXFP1SLC6A2PDE4DKCNH2HTR2A | |
| Florifenine SCHEMBL379372 | 0.99 | SLC6A2 (0.49) | RXFP1SLC6A2PDE4DKCNH2HTR2A | |
| SCHEMBL10626075 | 0.95 | CYP1A2 (0.48) | RXFP1SLC6A2PDE4DKCNH2HTR2A | |
| SCHEMBL10510019 | 0.95 | CYP1A2 (0.48) | RXFP1SLC6A2PDE4DKCNH2HTR2A | |
| SCHEMBL10509149 | 0.94 | CYP1A2 (0.49) | RXFP1SLC6A2PDE4DKCNH2HTR2A | |
| Antrafenine SCHEMBL29623495 | 0.89 | HTR4 (0.51) | SLC6A2PDE4DKCNH2HTR2AOPRK1 | |
| Antrafenine SCHEMBL24297 | 0.89 | HTR4 (0.51) | SLC6A2PDE4DKCNH2HTR2AOPRK1 | |
| SCHEMBL10510990 | 0.87 | CYP3A4 (0.48) | SLC6A2PDE4DKCNH2CYP1A2CYP2C9 | |
| SCHEMBL10509334 | 0.87 | CYP3A4 (0.63) | SLC6A2PDE4DKCNH2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094065-B1 | 2-AMINOBENZOIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | FERRER INTERNACIONAL, S.A. (ES) | 1989-12-20 | — | — | EP | disclosed |
| US-4767767-A | ANALGESIC, ANTIINFLAMMATORY AGENT | FERRER INTERNACIONAL S.A. (ES) | 1988-08-30 | — | — | US | disclosed |
| EP-0094065-A2 | 2-Aminobenzoic acid derivatives, a process for their preparation and pharmaceutical compositions | FERRER INTERNACIONAL, S.A. (ES) | 1983-11-16 | — | — | EP | disclosed |