SCHEMBL10511697

SCHEMBL10511697

CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1C=C[C@H](n2ccc(N=CN(C)C)nc2=O)O1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 2/20 0.42
DUT P33316 1/20 0.34
LPAR1 Q92633 1/20 0.33
TERT O14746 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10511694 1.00 NLRP3 (0.42) NLRP3DUTLPAR1TERT
SCHEMBL10512132 1.00 NLRP3 (0.42) NLRP3DUTLPAR1TERT
SCHEMBL10511053 0.93 NLRP3 (0.39) NLRP3DUTTERT
SCHEMBL10511339 0.86 DUT (0.36) NLRP3DUT
SCHEMBL10512762 0.84 DUT (0.35) DUT
SCHEMBL10511023 0.83 HRAS (0.41) DUT
SCHEMBL10508220 0.82 NLRP3 (0.38) NLRP3LPAR1
SCHEMBL10512510 0.82 NLRP3 (0.38) NLRP3LPAR1
SCHEMBL10508226 0.82 NLRP3 (0.38) NLRP3LPAR1
SCHEMBL10512514 0.82 NLRP3 (0.38) NLRP3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311100-A2 Derivatives of dideoxycytidine, their preparation and pharmaceutical use F. HOFFMANN-LA ROCHE AG (CH) 1989-04-12 EP disclosed