Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14945698 | 0.82 | DGAT1 (0.34) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL12033651 | 0.80 | DGAT1 (0.33) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL17643549 | 0.80 | CYP2D6 (0.37) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL3283444 | 0.78 | CYP2D6 (0.33) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL14465844 | 0.78 | HDAC3 (0.35) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL362095 | 0.77 | HDAC3 (0.34) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL2889944 | 0.77 | CYP2D6 (0.35) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL3610450 | 0.75 | KEAP1 (0.34) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL2151811 | 0.75 | CYP2D6 (0.31) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL2152110 | 0.75 | CYP2D6 (0.34) | DGAT1CYP2D6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305320-A2 | Multinucleic substituted complexants, complexes and complex salts, process for their preparation and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-01 | — | — | EP | disclosed |