Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855614 | 0.87 | HSD17B10 (0.49) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL2355780 | 0.87 | HSD17B10 (0.49) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL5171011 | 0.87 | HSD17B10 (0.49) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL1357066 | 0.83 | DPP4 (0.56) | HSD17B10CTSK | |
| SCHEMBL240005 | 0.83 | DPP4 (0.56) | HSD17B10CTSK | |
| SCHEMBL7380781 | 0.83 | HPGD (0.48) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL3188564 | 0.83 | HSD17B10 (0.55) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL231219 | 0.83 | HSD17B10 (0.55) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL889059 | 0.83 | HSD17B10 (0.55) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL2896482 | 0.83 | DPP4 (0.56) | HSD17B10CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310918-A2 | Peptide-like amino-acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-04-12 | — | — | EP | claimed |