Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355780 | 1.00 | HSD17B10 (0.49) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL5171011 | 1.00 | HSD17B10 (0.49) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL9555116 | 0.95 | HPGD (0.48) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL7380781 | 0.95 | HPGD (0.48) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL9554546 | 0.90 | CTSK (0.42) | HSD17B10HPGDCTSKSMN1; SMN2ALDH1A1 | |
| SCHEMBL10512917 | 0.87 | HSD17B10 (0.47) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL889059 | 0.85 | HSD17B10 (0.55) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL231219 | 0.85 | HSD17B10 (0.55) | HSD17B10HPGDCTSKSMN1; SMN2NPC1 | |
| SCHEMBL240005 | 0.85 | DPP4 (0.56) | HSD17B10CTSK | |
| SCHEMBL1357066 | 0.85 | DPP4 (0.56) | HSD17B10CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111562720-B | Photo-sensitized chemically amplified resist material, pattern forming method, semiconductor device, mask for lithography, and template for nanoimprint | 东京毅力科创株式会社 | 2023-09-29 | — | — | CN | disclosed |
| EP-1144403-A1 | SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000031063-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-06-02 | — | — | WO | disclosed |