SCHEMBL10513640

SCHEMBL10513640

CCOC(=O)c1cnn(-c2ncccc2Cl)c1S(N)(=O)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.50
HPGD P15428 2/20 0.50
NPC1 O15118 2/20 0.50
TP53 P04637 1/20 0.50
HTT P42858 1/20 0.47
ALDH1A1 P00352 7/20 0.46
HSD11B1 P28845 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
TSHR P16473 2/20 0.42
CHRNA7 P36544 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA5A P35218 1/20 0.41
ELANE P08246 1/20 0.41
KMT2A Q03164 2/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10513853 0.89 RAB9A (0.52) RAB9AHPGDNPC1TP53HTT
SCHEMBL10514660 0.87 RAB9A (0.50) RAB9AHPGDNPC1TP53HTT
SCHEMBL10514609 0.84 NPC1 (0.66) RAB9AHPGDNPC1TP53HTT
SCHEMBL10554970 0.84 RAB9A (0.53) RAB9AHPGDNPC1TP53HTT
SCHEMBL22558034 0.84 RAB9A (0.53) RAB9AHPGDNPC1TP53HTT
SCHEMBL10515032 0.84 HTT (0.47) RAB9AHPGDNPC1TP53HTT
SCHEMBL10514983 0.83 RAB9A (0.54) RAB9AHPGDNPC1TP53HTT
SCHEMBL10514673 0.82 HPGD (0.51) RAB9AHPGDNPC1TP53HTT
SCHEMBL10519327 0.81 HPGD (0.71) RAB9AHPGDNPC1TP53HTT
SCHEMBL10523687 0.81 HPGD (0.52) RAB9AHPGDNPC1TP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4881965-A CONTROLLING WILD OATS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1989-11-21 US disclosed
EP-0318602-A1 Pyrazolesulfonamide derivative, process for its production and herbicide containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-06-07 EP disclosed
CN-86100911-A The preparation method of pyrazoles sulfone amide derivative and the weedicide that contains this kind derivative 1986-09-24 CN disclosed
EP-0189069-A2 Pyrazolesulfonamide derivative, process for its production and herbicide containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-07-30 EP disclosed