SCHEMBL22558034

SCHEMBL22558034

CCOC(=O)c1cnn(-c2ncccc2Cl)c1C

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.53
NPC1 O15118 3/20 0.53
HPGD P15428 2/20 0.53
TP53 P04637 1/20 0.53
HTT P42858 1/20 0.49
MAPT P10636 2/20 0.48
ALDH1A1 P00352 7/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
KMT2A Q03164 1/20 0.48
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
ELANE P08246 1/20 0.45
HSD11B1 P28845 1/20 0.45
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
PDE4B Q07343 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10554970 0.90 RAB9A (0.53) RAB9ANPC1HPGDTP53HTT
SCHEMBL10514673 0.88 HPGD (0.51) RAB9ANPC1HPGDTP53HTT
SCHEMBL10514609 0.88 NPC1 (0.66) RAB9ANPC1HPGDTP53HTT
SCHEMBL31377059 0.85 HPGD (0.52) RAB9ANPC1HPGDTP53HTT
SCHEMBL10513640 0.84 RAB9A (0.50) RAB9ANPC1HPGDTP53HTT
SCHEMBL7233447 0.83 MAPK1 (0.55) RAB9ANPC1HPGDMAPTALDH1A1
SCHEMBL8343589 0.82 HTT (0.56) RAB9ANPC1HPGDTP53HTT
SCHEMBL15167552 0.81 HTT (0.50) RAB9ANPC1HPGDTP53HTT
SCHEMBL15167674 0.81 HTT (0.47) RAB9ANPC1HPGDTP53HTT
SCHEMBL8339620 0.81 PDE4B (0.62) RAB9ANPC1HPGDTP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874356-B Preparation of substituted pyrazoles and use thereof as precursors of anthranilamides 安道麦马克西姆有限公司 2025-04-08 CN disclosed
EP-3956314-A1 PREPARATION OF SUBSTITUTED PYRAZOLES AND THEIR USE AS ANTHRANILAMIDES PRECURSORS Adama Makhteshim Ltd. (IL) 2022-02-23 EP disclosed
WO-2020212991-A1 PREPARATION OF SUBSTITUTED PYRAZOLES AND THEIR USE AS ANTHRANILAMIDES PRECURSORS ADAMA MAKHTESHIM LTD. (IL) 2020-10-22 WO disclosed