Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055291 | 0.83 | ALDH1A1 (0.47) | ALDH1A1RAB9AMAPK1L3MBTL1ATM | |
| SCHEMBL27769196 | 0.76 | RAB9A (0.58) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL4495815 | 0.74 | RAB9A (0.57) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 | |
| SCHEMBL8385774 | 0.74 | RAB9A (0.62) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 | |
| SCHEMBL11147565 | 0.74 | RAB9A (0.62) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 | |
| SCHEMBL6159545 | 0.73 | TDP1 (0.48) | ALDH1A1RAB9AMAPK1L3MBTL1ATM | |
| SCHEMBL15388876 | 0.73 | RAB9A (0.61) | ALDH1A1RAB9AMAPK1L3MBTL1MAPT | |
| SCHEMBL10429412 | 0.73 | RAB9A (0.61) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 | |
| SCHEMBL10429413 | 0.73 | RAB9A (0.61) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 | |
| SCHEMBL27675512 | 0.73 | RAB9A (0.61) | ALDH1A1RAB9AMAPK1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345997-A2 | Azetidinone intermediates for 1-carba (dethia) cephalosporins | ELI LILLY AND COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |