Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 8/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 7/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | GCLC | P48506 | 2/20 | 0.39 |
| ▸ | IARS1 | P41252 | 4/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19361328 | 0.84 | IARS1 (0.41) | IARS1 | |
| SCHEMBL23408814 | 0.84 | IARS1 (0.41) | IARS1 | |
| SCHEMBL27427521 | 0.82 | SLC7A5 (0.45) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL6033505 | 0.82 | SLC7A5 (0.45) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL1537446 | 0.82 | SLC1A3 (0.41) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 | |
| SCHEMBL22392169 | 0.81 | IARS1 (0.38) | NOS3NOS1NOS2IARS1 | |
| SCHEMBL196042 | 0.80 | IARS1 (0.43) | IARS1 | |
| SCHEMBL19366508 | 0.80 | IARS1 (0.43) | IARS1 | |
| SCHEMBL196043 | 0.80 | IARS1 (0.43) | IARS1 | |
| SCHEMBL4385421 | 0.79 | SLC1A1 (0.43) | SLC1A2SLC1A3SLC1A1SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304954-A2 | Cyclic dipeptide enantiomers | ICI AUSTRALIA LIMITED (AU) | 1989-03-01 | — | — | EP | claimed |
| WO-2014134493-A1 | BROAD SPECTRUM ANTIBIOTIC COMPOUNDS AND USE THEREOF | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2014-09-04 | — | — | WO | disclosed |