Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IARS1 | P41252 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 10/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23408814 | 0.82 | IARS1 (0.41) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL19361328 | 0.82 | IARS1 (0.41) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL10514022 | 0.81 | SLC1A2 (0.43) | IARS1NOS1NOS3NOS2 | |
| SCHEMBL19366508 | 0.78 | IARS1 (0.43) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL196043 | 0.78 | IARS1 (0.43) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL196042 | 0.78 | IARS1 (0.43) | IARS1DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL10437071 | 0.77 | IARS1 (0.42) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL22393382 | 0.77 | IARS1 (0.45) | IARS1DPP4DPP8DPP9DPP7 | |
| SCHEMBL22392039 | 0.76 | SLC7A5 (0.44) | DPP4 | |
| SCHEMBL7366588 | 0.75 | ALDH1A1 (0.47) | IARS1DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530298-B2 | Poly(phosphoesters) for delivery of nucleic acids | TRANSLATE BIO, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| US-20200277446-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | TRANSLATE BIO, INC. | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277446-A1 | POLY(PHOSPHOESTERS) FOR DELIVERY OF NUCLEIC ACIDS | POLR2E, POLR2H, POLR1A | IARS1 127/4885DPP4 4201/4885DPP8 3638/4885 |
| US-11530298-B2 | Poly(phosphoesters) for delivery of nucleic acids | POLR2E, POLR2H, POLR1A | IARS1 127/4885DPP4 4201/4885DPP8 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.