Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.45 |
| ▸ | DRD1 | P21728 | 6/20 | 0.44 |
| ▸ | DRD5 | P21918 | 6/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511673 | 0.90 | HRH1 (0.42) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL10515200 | 0.90 | HRH1 (0.45) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL9774220 | 0.86 | ACE (0.47) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL9774141 | 0.82 | HRH1 (0.43) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL10515667 | 0.78 | HRH1 (0.42) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL10513313 | 0.78 | HRH1 (0.44) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL10512016 | 0.77 | KDM4E (0.45) | L3MBTL1HPGDSMN1; SMN2LMNA | |
| SCHEMBL10515436 | 0.76 | DRD2 (0.48) | DRD1DRD3DRD2HPGDSMN1; SMN2 | |
| SCHEMBL10815339 | 0.74 | ACE (0.46) | CYP3A4LMNA | |
| SCHEMBL9774168 | 0.74 | KDM4E (0.45) | CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320753-A2 | Derivatives of cyclic aminoacids, their preparation, compounds containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-21 | — | — | EP | disclosed |