Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | ELOC | Q15369 | 1/20 | 0.33 |
| ▸ | ELOB | Q15370 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801129 | 0.69 | CA2 (0.47) | CA2LMNA | |
| SCHEMBL10512559 | 0.64 | CA2 (1.00) | CA2KDM4EALDH1A1HTTVHL | |
| SCHEMBL10514261 | 0.62 | CA2 (0.49) | CA2KDM4EALDH1A1HTTVHL | |
| SCHEMBL10512165 | 0.57 | CA2 (1.00) | CA2KDM4EALDH1A1HTTVHL | |
| SCHEMBL9539111 | 0.57 | CA2 (0.63) | CA2 | |
| SCHEMBL10699546 | 0.56 | CA2 (0.53) | CA2KDM4ELMNA | |
| SCHEMBL18007525 | 0.56 | CA2 (0.53) | CA2KDM4ELMNA | |
| SCHEMBL9607758 | 0.56 | KDM4E (0.56) | CA2KDM4EALDH1A1HTTVHL | |
| SCHEMBL8219509 | 0.54 | KDM4E (0.41) | CA2KDM4EALDH1A1HTTVHL | |
| SCHEMBL2775772 | 0.54 | KDM4E (0.63) | CA2KDM4EALDH1A1HTTVHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189690-B1 | SUBSTITUTED AROMATIC SULFONAMIDES, THEIR PREPARATION AND OPHTHALMIC COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1989-03-01 | — | — | EP | disclosed |