Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 8/20 | 0.36 |
| ▸ | PPARG | P37231 | 8/20 | 0.36 |
| ▸ | PPARD | Q03181 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511182 | 0.80 | CYP17A1 (0.40) | ALDH1A1PPARAPPARGPPARDKDM4E | |
| SCHEMBL9273734 | 0.78 | KDM4E (0.36) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL10512810 | 0.78 | HTT (0.38) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL9827198 | 0.75 | POLB (0.41) | PPARAPPARGPPARDKMT2AMEN1 | |
| SCHEMBL10808391 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL9836636 | 0.71 | PTGS2 (0.47) | ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD | |
| SCHEMBL10512831 | 0.70 | GPBAR1 (0.35) | KDM4ECYP1A2 | |
| SCHEMBL10513130 | 0.69 | POLB (0.43) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL9827847 | 0.68 | PPARG (0.42) | PPARAPPARGPPARD | |
| SCHEMBL10512118 | 0.68 | POLB (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62228081-A | — | — | None | — | — | JP | disclosed |
| EP-0205872-B1 | FUROBENZISOXAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-4791209-A | DIURETICS, HYPOTENSIVE AGENTS | Chugai Seiyako Kabushiki Kaisha (JP) | 1988-12-13 | — | — | US | disclosed |
| JP-S62228081-A | FUROBENZISOXAZOLE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1987-10-06 | — | — | JP | disclosed |
| EP-0205872-A1 | Furobenzisoxazole derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-12-30 | — | — | EP | disclosed |