Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LRP6 | O75581 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | DKK1 | O94907 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241447 | 0.81 | RXRA (0.49) | ALDH1A1KDM4EGAAL3MBTL1SRC | |
| SCHEMBL30966772 | 0.80 | SLC16A3 (0.50) | SLC16A3ALDH1A1KDM4EMYCMEN1 | |
| SCHEMBL8646935 | 0.77 | SLC16A3 (0.51) | SLC16A3ALDH1A1KDM4EL3MBTL1MYC | |
| SCHEMBL1821912 | 0.77 | SRC (0.59) | ALDH1A1KDM4EGAASRCMEN1 | |
| SCHEMBL5535026 | 0.76 | G6PD (0.49) | ALDH1A1GAAL3MBTL1SRCMEN1 | |
| SCHEMBL16227423 | 0.76 | POLQ (0.52) | — | |
| SCHEMBL7601521 | 0.75 | SLC16A3 (0.46) | SLC16A3ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL41899 | 0.75 | SLC16A3 (0.46) | SLC16A3ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL3255867 | 0.75 | SLC16A3 (0.43) | SLC16A3ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL3305470 | 0.75 | SLC16A3 (0.43) | SLC16A3ALDH1A1KDM4EMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299663-A2 | Antihistaminic aromatic tetrahydroazepinones (and thiones) | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |
| US-4746657-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1988-05-24 | — | — | US | disclosed |
| US-4335129-A | ANALGESIC, ANTIINFLAMMATORY | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1982-06-15 | — | — | US | disclosed |
| US-4329455-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-05-11 | — | — | US | disclosed |
| US-4163844-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-08-07 | — | — | US | disclosed |