Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555568 | 0.87 | PTGS2 (0.71) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| SCHEMBL13444612 | 0.86 | CDC25B (0.60) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| SCHEMBL10720480 | 0.84 | POLB (0.46) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| Hydrochloric Acid SCHEMBL10874909 | 0.83 | POLB (0.44) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| SCHEMBL22169241 | 0.82 | CLCN2 (0.71) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| SCHEMBL7851667 | 0.82 | PTGS2 (0.73) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| Hydrochloric Acid SCHEMBL10720951 | 0.82 | POLB (0.43) | PTGS2KMT2AMEN1AKR1B10ABCB11 | |
| SCHEMBL20916302 | 0.82 | MAPT (0.55) | PTGS2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL22169135 | 0.81 | FABP3 (0.54) | KMT2AMEN1AKR1C3AKR1C2TRPA1 | |
| SCHEMBL28277819 | 0.81 | PTGS2 (0.59) | PTGS2KMT2AMEN1AKR1B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309422-A2 | New amidino tricycle derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |