Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.71 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.71 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.71 |
| ▸ | DHFR | P00374 | 1/20 | 0.71 |
| ▸ | MPO | P05164 | 1/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851667 | 0.95 | PTGS2 (0.73) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL6141200 | 0.92 | PTGS2 (0.73) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL10516618 | 0.87 | PTGS2 (0.55) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL3500411 | 0.87 | FTO (0.72) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL3364068 | 0.84 | POLB (0.60) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL7570755 | 0.84 | CLCN2 (0.60) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL1186480 | 0.84 | AKR1C3 (0.77) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL29834970 | 0.84 | AKR1C3 (0.77) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL28277819 | 0.84 | PTGS2 (0.59) | PTGS2KMT2AMEN1AKR1C3CYP3A4 | |
| SCHEMBL11106473 | 0.83 | AKR1C3 (0.67) | PTGS2KMT2AMEN1AKR1C3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934277-A1 | PROCESS FOR THE PREPARATION OF N- 2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017649-A1 | PROCESS FOR THE PREPARATION OF N-[2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |
| EP-0039224-B1 | COMPOUND HAVING ANTITUMOUR PROPERTIES | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1984-06-27 | — | — | EP | disclosed |
| US-4366318-A | 4'-/9-/4-/N-NETHYLCARBOXAMIDO/-5-METHYL/ACRYDINYLAMINO/ METHANESULFON-M-ANISIDIDE OR SALT | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1982-12-28 | — | — | US | disclosed |
| EP-0039224-A2 | Compound having antitumour properties | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1981-11-04 | — | — | EP | disclosed |
| US-4092426-A | LIVER DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1978-05-30 | — | — | US | disclosed |