Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | DRD5 | P21918 | 1/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10515020 | 0.93 | — | — | |
| SCHEMBL9727711 | 0.93 | CHRM2 (0.75) | CHRM2CHRM1CHRM4CHRM5ALOX15 | |
| SCHEMBL11445663 | 0.91 | LMNA (0.68) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL11445773 | 0.90 | USP2 (0.67) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9727789 | 0.90 | CHRM2 (0.73) | CHRM2CHRM1CHRM4CHRM5ALOX15 | |
| SCHEMBL9676282 | 0.89 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM5ALOX15 | |
| SCHEMBL10516563 | 0.89 | — | — | |
| SCHEMBL10516173 | 0.89 | — | — | |
| SCHEMBL10359937 | 0.89 | — | — | |
| SCHEMBL10515636 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345629-A2 | Condensed diazepinones, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1989-12-13 | — | — | EP | disclosed |